Product information
Size
1 g
Catalog number
SIH-308-1G
Price
85 EUR
More information
Stock availabilitIn Stock
In Stock
CAS number
152-11-4
Description
L-type Ca channel blocker
Molecular weight
491,07 g/mol
Primary research fields
Neuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
Other name
2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
Product category
Small Molecules
Product type
Inhibitor
Chemical formula
C27H38N2O4•HCl
Origin
Synthetic
Purity pourcentage
>98%
Soluble in
Soluble to 100 mM in ethanol and to 50 mM in water
Physical appearance
White Solid
Storage recommendations
-20ºC
Shipping recommendations
Shipped Ambient
Safety information
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed R60 - May impair fertility R61 - May cause harm to the unborn child R68 - Possible risk of irreversible effects Hazard Phrases: H301-H311-H331 Precautionary Phrases: P261-P280-P301 + P310-P311
PubChem number
62969
Scientific context
Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches. Its mechanism is to block voltage-dependent calcium channels (1).
Bibliography
1. Livesley B., and Oram S. (1972) Br Med J. 2(5804): 50.
Release date
8-Apr-2011
PubMed number
Refer to PubMed
Tested applications
To be tested
Tested reactivity
To be tested
Representative figure legend
Chemical structure of Verapamil HCl (SIH-308), a L-type Ca channel blocker. CAS #: 152-11-4. Molecular Formula: C27H38N2O4.HCl. Molecular Weight: 491.07 g/mol. Chemical structure of Verapamil HCl, a L-type Ca channel blocker (SIH-308). CAS # 152-11-4. Molecular Formula: C27H38N2O4.HCl.
Warning information
Non-hazardous
Country of production
Canada
Total weight (kg)
0.25
Net weight (g)
1