OVA Conjugated Trefoil Factor 3, Intestinal (TFF3)

Product information

Size

50ug

Catalog number

CPB656Ra21

Price

480 EUR

More information

Source

Protein conjugation

Predicted Molecular Mass(KD)

NA

Accurate Molecular Mass(KD)

NA

Organism species

Rattus norvegicus (Rat)

Item Name

Trefoil Factor 3, Intestinal

Alternative Names

HITF; ITF3; TFI; HP1.B

Research Area

Tumor immunity;Gastroenterology;

Buffer Formulation

PBS, pH7.4.

Traits

Freeze-dried powder

Purity

> 90%

Protein length

Ser29-Asp42

Tag

N-terminal His Tag

Expression System

Protein conjugation

Application

Immunogen; SDS-PAGE; WB.

Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.