Human TRAIL/Apo2L, Recombinant[TRAIL (TNF Related Apoptosis Inducing Ligand)/Apo 2 Ligand, Recombinant]

Product information

Size

NA

Catalog number

MBS319021

Price

5 EUR

More information

Products_type

Recombinant Protein

Reactivity

Human

Description

This 1 is suited for programmed cell-death studies.FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Source

Recombinants or rec. proteins

Group

recombinants

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNF╬▒, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.