Product information
Size
100ug
Catalog number
GEN631797
Price
912 EUR
More information
Also known as
STAT 6
Other names
signal transducer and activator of transcription 6 isoform 1; Signal transducer and activator of transcription 6; signal transducer and activator of transcription 6; STAT, interleukin4-induced; transcription factor IL-4 STAT; signal transducer and activator of transcription 6, interleukin-4 induced; IL-4 Stat
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Gene name synonims
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Other gene names
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Clonality
Monoclonal
Immunoglobulin isotype
IgG1
Clone
9L666
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes activated human STAT6 phosphorylated at Tyrosine 641 at ~97kD. The antibody does not cross react with the non-phosphorylated form of STAT6 nor with unrelated phosphorylation sites. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Purified by thiophilic adsorption and size exclusion chromatography.
Form/Appearance
Supplied as a lyophilized powder from 2X PBS, PEG, sucrose, 0.09% sodium azide. Reconstitute with 1ml sterile, ddH2O.
Concentration
N/A
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile ddH2O, sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested applications:
ELISA (EL/EIA), Western Blot (WB)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
French translation
anticorps