STAT 6, phosphorylated (STAT6B, STAT6C, D12S1644, IL-4-STAT, IL 4 induced STAT, Signal Transducer and Activator of Transcription 6)

Product information

Size

100ug

Catalog number

GEN633383

Price

636 EUR

More information

Also known as

STAT 6

Other names

signal transducer and activator of transcription 6 isoform 1; Signal transducer and activator of transcription 6; signal transducer and activator of transcription 6; STAT, interleukin4-induced; transcription factor IL-4 STAT; signal transducer and activator of transcription 6, interleukin-4 induced; IL-4 Stat

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A

Gene name synonims

STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A

Other gene names

STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A

Clonality

Monoclonal

Immunoglobulin isotype

IgG1

Clone

4i61

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes phosphorylated STAT6, Mr 100kD. Species Crossreactivity: Human, mouse and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Highly Puri ed by subsequent thiophilic adsoption and size exclusion chromatography.

Form/Appearance

Supplied as a liquid in ~143ul of PBS, 0.09% sodium azide before the addition of glycerol to 30%.

Concentration

N/A

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested applications:

ELISA (EL/EIA), Western Blot (WB)

Description

Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.