Product information
Size
100ug
Catalog number
GEN633383
Price
636 EUR
More information
Also known as
STAT 6
Other names
signal transducer and activator of transcription 6 isoform 1; Signal transducer and activator of transcription 6; signal transducer and activator of transcription 6; STAT, interleukin4-induced; transcription factor IL-4 STAT; signal transducer and activator of transcription 6, interleukin-4 induced; IL-4 Stat
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Gene name synonims
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Other gene names
STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT; N/A
Clonality
Monoclonal
Immunoglobulin isotype
IgG1
Clone
4i61
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes phosphorylated STAT6, Mr 100kD. Species Crossreactivity: Human, mouse and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Highly Puri ed by subsequent thiophilic adsoption and size exclusion chromatography.
Form/Appearance
Supplied as a liquid in ~143ul of PBS, 0.09% sodium azide before the addition of glycerol to 30%.
Concentration
N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested applications:
ELISA (EL/EIA), Western Blot (WB)
Description
Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.