Product information
Size
100ug
Catalog number
GEN438346
Price
354 EUR
More information
Also known as
Eosinophil Peroxidase
Other names
eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase; N/A
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
EPX
Gene name synonims
N/A
Other gene names
EPX; EPX; EPO; EPP; EPX-PEN; EPER; EPO; EPP; EPO
Clonality
Monoclonal
Immunoglobulin isotype
IgG1, kappa
Clone
AHE-1
Host organism
Mouse (Mus musculus)
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
N/A
Form/Appearance
N/A
Concentration
N/A
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH)
Conjugate
Peroxidases with EC number 1.11.1.x are catalyzing the reaction of ROOR' + electron donor (2 eā) + 2H+ ā ROH + R'OH