Product information
Size
10µg
Catalog number
PKSH033196-10µg
Price
267 EUR
More information
Synonym
Uracil phosphoribosyltransferase homolog; UPP; FUR1; UPRT
Activity
NA
Sequence
Met1-Asp309
Fusion tag
N-6His
Accession
Q96BW1
Expressed Host
E.coli
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Purity
>95% as determined by reducing SDS-PAGE.
Endotoxin
<1.0 EU per µg as determined by LAL test.
Stability and Storage
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
Mol Mass
35.9 kDa
AP Mol Mass
40 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl pH 8.0.
Background
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source
Recombinants or rec. proteins
Group
recombinants