Desethyl Sacubitril

Product information

Size

2,5 mg

Catalog number

D288245

Price

224 EUR

More information

Chemical available in other sizes

Please inquire size and price

Stock availability

In Stock

Cas number

149709-44-4

Chemical's molecular weight

383.44

Chemical's main applications

Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Other name

[S-(R*,S*)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid; Sacubitrilat; LBQ 657

Chemical's formula

C22H25NO5

Physical properties

White Solid

Melting temperature

166-168°C

Boiling temperature

No Data Available

Chemical's soluble in

DMSO (Slightly), Methanol (Slightly)

Stability conditions

No Data Available

Storage

Refrigerator