CD130 (CDw130, gp130, GP130-RAPS, IL-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, IL 6 Signal Transducer, IL6ST, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha)

Product information

Size

100ug

Catalog number

GEN608958

Price

1078 EUR

More information

Also known as

CD130

Other names

N/A

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

N/A

Gene name synonims

N/A

Other gene names

N/A

Clonality

Monoclonal

Immunoglobulin isotype

IgG1

Clone

B-T2

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes human CD130, soluble and membrane bound gp130 receptor. This antibody has been reported to block the activity of IL-6.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Purified

Form/Appearance

Supplied as a liquid in PBS, 0.09% sodium azide.

Concentration

N/A

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Tested applications:

ELISA (EL/EIA), Flow Cytometry (FC/FACS)

Description

The CD130 (CDw130, gp130, GP130-RAPS, IL-6 Receptor Subunit beta, IL-6 Receptor Subunit beta, IL-6R Subunit beta, IL6R-beta, IL-6R-beta, IL-6RB, IL 6 Signal Transducer, IL6ST, Glycoprotein 130, Oncostatin-M Receptor Subunit alpha) is a α- or alpha protein sometimes glycoprotein present in blood.Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. ,The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.