Eosinophil Major Basic Protein

Product information

Size

100ug

Catalog number

GEN605399

Price

569 EUR

More information

Also known as

Eosinophil Major Basic Protein

Other names

eosinophil major basic protein; Bone marrow proteoglycan; bone marrow proteoglycan; OTTHUMP00000234774; OTTHUMP00000234775; OTTHUMP00000234776; bone-marrow proteoglycan; proteoglycan 2 preproprotein; natural killer cell activator; eosinophil major basic protein; eosinophil granule major basic protein; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); Proteoglycan 2Cleaved into the following chain:Eosinophil granule major basic protein; EMBP; MBP; Alternative name(s):; Pregnancy-associated major basic protein

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP

Gene name synonims

PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP

Other gene names

PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP

Clonality

Monoclonal

Immunoglobulin isotype

IgG1

Clone

1.B.787

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes human eosinophil major basic protein (14kD) irrespective of the stages of eosinophil activation and can be regarded as a "pan-eosinophil" marker. Recognizes the secreted pro-form of MBP (Pregnancy associated MBP, 23.8kD) and the mature form found in the matrix of the eosinophil large specific granule (13.8kD). Does not crossreact with equine, mouse or rat MBP.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Affinity Purified by Protein A affinity chromatography.

Form/Appearance

Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 10mM sodium azide.

Concentration

N/A

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Tested applications:

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Description

Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.