Product information
Size
100ug
Catalog number
GEN605399
Price
569 EUR
More information
Also known as
Eosinophil Major Basic Protein
Other names
eosinophil major basic protein; Bone marrow proteoglycan; bone marrow proteoglycan; OTTHUMP00000234774; OTTHUMP00000234775; OTTHUMP00000234776; bone-marrow proteoglycan; proteoglycan 2 preproprotein; natural killer cell activator; eosinophil major basic protein; eosinophil granule major basic protein; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); Proteoglycan 2Cleaved into the following chain:Eosinophil granule major basic protein; EMBP; MBP; Alternative name(s):; Pregnancy-associated major basic protein
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP
Gene name synonims
PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP
Other gene names
PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP
Clonality
Monoclonal
Immunoglobulin isotype
IgG1
Clone
1.B.787
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human eosinophil major basic protein (14kD) irrespective of the stages of eosinophil activation and can be regarded as a "pan-eosinophil" marker. Recognizes the secreted pro-form of MBP (Pregnancy associated MBP, 23.8kD) and the mature form found in the matrix of the eosinophil large specific granule (13.8kD). Does not crossreact with equine, mouse or rat MBP.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Affinity Purified by Protein A affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 10mM sodium azide.
Concentration
N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested applications:
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Description
Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.