DcTRAIL-R1 (Decoy TRAIL Receptor 1, TNFRH1, mSOB)

Product information

Size

100ug

Catalog number

GEN600154

Price

614 EUR

More information

Also known as

DcTRAIL-R1

Other names

N/A

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

N/A

Gene name synonims

N/A

Other gene names

N/A

Clonality

Monoclonal

Immunoglobulin isotype

IgG2a

Clone

7H65

Host organism

Rat (Rattus norvegicus)

Source organism

Mouse (Mus musculus)

Species reactivity

Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Selected for its ability to detect mouse DcTRAIL R1 by immunohistochemistry. In Western Blots, this antibody shows less than 10% crossreactivity with rm4-1BB Ligand, rhBAFF R, rhDcTRAIL R3, rmFas, rmOPG, rhTRAIL R4 and does not crossreact with other proteins tested.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Affinity Purified by Protein G affinity chromatography.

Form/Appearance

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS, 40-50% glycerol. If 0.2ml is used, the concentration will be 0.5mg/ml.

Concentration

N/A

Storage and shipping

Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested applications:

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.