Recombinant Human Uracil Phosphoribosyltransferase Homolog/UPRT Protein(N-6His)

Product information

Size

10µg

Catalog number

PKSH033196-10µg

Price

267 EUR

More information

Synonym

Uracil phosphoribosyltransferase homolog; UPP; FUR1; UPRT

Activity

NA

Sequence

Met1-Asp309

Fusion tag

N-6His

Accession

Q96BW1

Expressed Host

E.coli

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Purity

>95% as determined by reducing SDS-PAGE.

Endotoxin

<1.0 EU per µg as determined by LAL test.

Stability and Storage

Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles

Mol Mass

35.9 kDa

AP Mol Mass

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl pH 8.0.

Background

UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer

Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Source

Recombinants or rec. proteins

Group

recombinants