Product information
Size
0.1ml
Catalog number
bs-2951R-Cy7
Price
350 EUR
More information
Long name
SQSTM1 Polyclonal Antibody, Cy7 Conjugated
Category
Conjugated Primary Antibodies
Conjugation
Cy7
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
SQSTM1
Specificity
This is a highly specific antibody against SQSTM1.
Modification
Unmodified
Modification site
None
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen_range
80-130/440
Subcellular location
Cytoplasm, Nucleus
Source
KLH conjugated synthetic peptide derived from human SQSTM1/Ubiquitin-binding protein p62
Gene ID number
8878
Swiss Prot
Q13501
Tested applications
IF(IHC-P)
Recommended dilutions
IF(IHC-P)(1:50-200)
Crossreactivity
Human, Mouse, Rat
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background
Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission
743nm/767nm
Synonyms
p60; p62; A170; OSIL; PDB3; ZIP3; p62B; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
Additional conjugation
Cy7
French translation
anticorps